SCHEMBL633352

SCHEMBL633352

CN1C2CCC1CC(c1ccccc1)C2

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 4/20 0.55
SLC6A3 Q01959 4/20 0.55
SLC6A4 P31645 3/20 0.54
SIGMAR1 Q99720 5/20 0.54
SLC18A3 Q16572 5/20 0.54
OPRM1 P35372 2/20 0.54
OPRL1 P41146 1/20 0.54
CHRM3 P20309 3/20 0.51
CHRM2 P08172 2/20 0.51
CHRM1 P11229 2/20 0.51
CHRM4 P08173 1/20 0.51
CHRM5 P08912 1/20 0.51
ADRA2A P08913 1/20 0.51
DRD2 P14416 1/20 0.51
ADRA2B P18089 1/20 0.51
ADRA2C P18825 1/20 0.51
DRD1 P21728 1/20 0.51
HRH2 P25021 1/20 0.51
ADRA1D P25100 1/20 0.51
HTR2A P28223 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1721954 1.00 SLC6A2 (0.55) SLC6A2SLC6A3SLC6A4SIGMAR1SLC18A3
SCHEMBL633351 1.00 SLC6A2 (0.55) SLC6A2SLC6A3SLC6A4SIGMAR1SLC18A3
SCHEMBL25803074 0.82 OPRM1 (0.58) SLC6A2SLC6A3SLC6A4SIGMAR1SLC18A3
SCHEMBL8205042 0.82 SLC6A2 (0.56) SLC6A2SLC6A3SLC6A4
SCHEMBL7458617 0.82 SLC6A2 (0.56) SLC6A2SLC6A3SLC6A4
SCHEMBL7352894 0.82 SLC6A2 (0.56) SLC6A2SLC6A3SLC6A4
SCHEMBL10194861 0.82 SLC6A2 (0.56) SLC6A2SLC6A3SLC6A4
SCHEMBL8812053 0.80 SLC6A4 (0.47) SLC6A2SLC6A3SLC6A4
SCHEMBL7560904 0.80 SLC6A2 (0.58) SLC6A2SLC6A3SLC6A4CHRM1DRD2
SCHEMBL7561589 0.80 SLC6A4 (0.47) SLC6A2SLC6A3SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 386 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
EP-4106872-A1 COMPOSITIONS AND METHODS FOR ASSESSING THE EFFICACY OF INHIBITORS OF NEUROTRANSMITTER TRANSPORTERS Denovo Biopharma LLC (US) 2022-12-28 EP claimed
CN-115515680-A Compositions and methods for assessing efficacy of neurotransmitter transporter inhibitors 索元生物医药有限公司 2022-12-23 CN claimed
EP-3558396-B1 DIFFERENTIAL DIAGNOSIS OF PARKINSON'S DISEASE GE HEALTHCARE LTD (GB) 2021-11-24 EP claimed
US-10980899-B2 Differential diagnosis GE HEALTHCARE LIMITED (GB) 2021-04-20 US claimed
US-20190328909-A1 DIFFERENTIAL DIAGNOSIS ACADEMIC MEDICAL CENTER (NL) 2019-10-31 US claimed
EP-3558396-A1 DIFFERENTIAL DIAGNOSIS OF PARKINSON'S DISEASE GE Healthcare Limited (GB) 2019-10-30 EP claimed
WO-2018115148-A1 DIFFERENTIAL DIAGNOSIS OF PARKINSON'S DISEASE GE HEALTHCARE LIMITED (GB) 2018-06-28 WO claimed
WO-2012056452-A2 PHARMACEUTICAL COMPOSITIONS AND DELIVERY DEVICES COMPRISING STINGING CELLS OR CAPSULES NANOCYTE (ISRAEL) LTD. (IL) 2012-05-03 WO claimed
EP-1590007-B1 IMPROVED RADIOMETAL COMPLEX COMPOSITIONS GE HEALTHCARE LTD (GB) 2010-11-10 EP claimed
US-20020159949-A1 Methods for diagnosing and monitoring treatment ADHD by assessing the dopamine transporter level THE GENERAL HOSPITAL CORPORATION 2002-10-31 US claimed
US-20020150535-A1 Methods for diagnosing and monitoring treatment ADHD by assessing the dopamine transporter level MADRAS BERTHA K (US) 2002-10-17 US claimed
EP-1196083-A1 IMAGING THE DOPAMINE TRANSPORTER TO DETERMINE AD-HD PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2002-04-17 EP claimed
WO-2001090717-A2 LINKER ARMS FOR NANOCRYSTALS AND COMPOUNDS THEREOF VANDERBILT UNIVERSITY (US) 2001-11-29 WO claimed
WO-2001090716-A2 LINKER ARMS FOR NANOCRYSTALS AND COMPOUNDS THEREOF VANDERBILT UNIVERSITY (US) 2001-11-29 WO claimed
US-20010020096-A1 Process for synthesizing anhydroecgonine derivative NIHON MEDI-PHYSICS CO., LTD. (JP) 2001-09-06 US claimed
EP-1127887-A1 Process for synthesizing anhydroecgonine derivative NIHON MEDI-PHYSICS Co., Ltd. (JP) 2001-08-29 EP claimed
WO-2001000082-A1 IMAGING THE DOPAMINE TRANSPORTER TO DETERMINE AD-HD PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2001-01-04 WO claimed
EP-0984965-A1 8-AZABICYCLO(3,2,1)OCT-2-ENE AND OCTANE DERIVATIVES AS CHOLINERGIC LIGANDS AT NICOTINIC ACH RECEPTORS NEUROSEARCH A/S (DK) 2000-03-15 EP claimed
WO-1998054181-A1 8-AZABICYCLO(3,2,1)OCT-2-ENE AND OCTANE DERIVATIVES AS CHOLINERGIC LIGANDS AT NICOTINIC ACH RECEPTORS NEUROSEARCH A/S (DK) 1998-12-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10980899-B2 Differential diagnosis PARK7, SNCA, PSPH SLC6A2 244/4885SLC6A3 51/4885SLC6A4 833/4885
US-20190328909-A1 DIFFERENTIAL DIAGNOSIS PARK7, SNCA, PSPH SLC6A2 244/4885SLC6A3 51/4885SLC6A4 833/4885
US-20020150535-A1 Methods for diagnosing and monitoring treatment ADHD by assessing the dopamine transporter level SLC6A3, SLC6A2, SLC18A2 SLC6A2 2/4885SLC6A3 1/4885SLC6A4 4/4885
US-20010020096-A1 Process for synthesizing anhydroecgonine derivative CES2, NPR1, OPRL1 SLC6A2 185/4885SLC6A3 385/4885SLC6A4 908/4885
US-20020159949-A1 Methods for diagnosing and monitoring treatment ADHD by assessing the dopamine transporter level SLC6A3, SLC6A2, SLC18A2 SLC6A2 2/4885SLC6A3 1/4885SLC6A4 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.