Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16519665 | 0.90 | CA12 (0.49) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL16796406 | 0.90 | CA12 (0.49) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL8611221 | 0.88 | LMNA (0.49) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL8434086 | 0.88 | CA12 (0.48) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL2849989 | 0.88 | CA12 (0.53) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL2849983 | 0.88 | CA12 (0.53) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL18169504 | 0.87 | CA12 (0.47) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL18169505 | 0.87 | CA12 (0.47) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL13906649 | 0.87 | CA12 (0.47) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL6934998 | 0.86 | ALDH1A1 (0.59) | CA12CA1CA2CA9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008151306-A1 | SYNTHESIS OF CYCLODEPSIPEPTIDE COMPOUNDS HAVING ANTINEOPLASTIC AND/OR ANTIMICROBIAL ACTIVITY | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2008-12-11 | — | — | WO | disclosed |