Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 4/20 | 0.54 |
| ▸ | CA9 | Q16790 | 4/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SLC18A1 | P54219 | 1/20 | 0.48 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8106893 | 0.87 | ALDH1A1 (0.62) | PIM1CA12CA9CA1ALDH1A1 | |
| SCHEMBL28069506 | 0.83 | CA12 (0.61) | PIM1CA12CA9CA1ALDH1A1 | |
| SCHEMBL8116374 | 0.83 | ALDH1A1 (0.57) | PIM1CA12CA9CA1ALDH1A1 | |
| SCHEMBL8115226 | 0.80 | CA12 (0.58) | PIM1CA12CA9CA1ALDH1A1 | |
| SCHEMBL27903484 | 0.79 | ALDH1A1 (0.53) | PIM1CA12CA9CA1ALDH1A1 | |
| SCHEMBL11223798 | 0.78 | PIM1 (0.53) | PIM1CA12CA9CA1ALDH1A1 | |
| SCHEMBL11237543 | 0.78 | PIM1 (0.49) | PIM1CA12CA9CA1ALDH1A1 | |
| SCHEMBL2490464 | 0.77 | PIM1 (0.64) | PIM1CA12CA9CA1ALDH1A1 | |
| SCHEMBL31290722 | 0.77 | PIM1 (0.64) | PIM1CA12CA9CA1ALDH1A1 | |
| SCHEMBL11223795 | 0.77 | PIM1 (0.51) | PIM1CA12CA9CA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |