SCHEMBL8106893

SCHEMBL8106893

CNc1ccc2c(O)cc(=O)oc2c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.62
KDM4E B2RXH2 6/20 0.62
KMT2A Q03164 2/20 0.62
SLC18A1 P54219 1/20 0.58
SLC18A2 Q05940 1/20 0.58
CA12 O43570 6/20 0.54
CA9 Q16790 6/20 0.54
CA1 P00915 4/20 0.54
MEN1 O00255 1/20 0.54
MAPT P10636 1/20 0.54
MAOB P27338 2/20 0.48
ALB P02768 1/20 0.48
HPGD P15428 5/20 0.47
HSD17B10 Q99714 4/20 0.47
CASP1 P29466 2/20 0.47
CASP7 P55210 2/20 0.47
LMNA P02545 2/20 0.47
POLB P06746 1/20 0.47
RECQL P46063 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8107352 0.87 PIM1 (0.58) ALDH1A1KDM4EKMT2ASLC18A1SLC18A2
SCHEMBL8121374 0.83 ALDH1A1 (0.69) ALDH1A1KDM4EKMT2ASLC18A1SLC18A2
SCHEMBL3361958 0.81 ALDH1A1 (0.68) ALDH1A1KDM4EKMT2ASLC18A1SLC18A2
SCHEMBL25603199 0.80 ALDH1A1 (0.58) ALDH1A1KDM4EKMT2ACA12CA9
SCHEMBL8121591 0.80 ALDH1A1 (0.69) ALDH1A1KDM4EKMT2ACA12CA9
SCHEMBL11227890 0.78 CA12 (0.52) ALDH1A1KDM4EKMT2ACA12CA9
SCHEMBL16582394 0.77 ALDH1A1 (0.68) ALDH1A1KDM4EKMT2ACA12CA9
SCHEMBL757926 0.77 ALDH1A1 (0.68) ALDH1A1KDM4EKMT2ACA12CA9
SCHEMBL31290721 0.77 ALDH1A1 (0.68) ALDH1A1KDM4EKMT2ACA12CA9
SCHEMBL29419327 0.77 ALDH1A1 (1.00) ALDH1A1KDM4EKMT2ACA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6114546-A Aminomethylene derivatives and ultraviolet absorbent comprising thereof CHEMIPRO KASEI KAISHA, LIMITED (JP) 2000-09-05 US disclosed
EP-0950655-A1 AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME CHEMIPRO KASEI KAISHA, LIMITED (JP) 1999-10-20 EP disclosed