Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.65 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.65 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.60 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.60 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.60 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17117410 | 0.83 | PLAAT3 (0.72) | MTNR1AMTNR1BPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL13097760 | 0.82 | MTNR1A (0.57) | MTNR1AMTNR1BPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL8100512 | 0.81 | HTT (0.60) | MTNR1AMTNR1BHTTKMT2AMEN1 | |
| SCHEMBL16804701 | 0.81 | HTT (0.62) | PLAAT3PLAAT5PLAAT2PLAAT4ALDH1A1 | |
| SCHEMBL16804706 | 0.81 | HTT (0.62) | HTTL3MBTL1TGM2 | |
| SCHEMBL917677 | 0.81 | HTT (0.65) | PLAAT3PLAAT5PLAAT2PLAAT4HTT | |
| SCHEMBL6748819 | 0.80 | HTT (0.72) | HTTKMT2AL3MBTL1TGM2KDM4E | |
| SCHEMBL18254066 | 0.80 | HTT (0.81) | HTTKMT2AL3MBTL1TGM2 | |
| SCHEMBL16804702 | 0.80 | HTT (0.60) | HTTKMT2AMEN1L3MBTL1TGM2 | |
| SCHEMBL10110752 | 0.80 | HTT (0.54) | ALDH1A1HTTKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008153902-A2 | UROTENSIN II RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-12-18 | — | — | WO | disclosed |