Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 3/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687407 | 0.99 | TMEM97 (0.44) | TMEM97SIGMAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL5158515 | 0.95 | TMEM97 (0.42) | TMEM97SIGMAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL6360325 | 0.86 | MAPT (0.43) | SLC6A2SLC6A4SLC6A3PRKDCALDH1A1 | |
| SCHEMBL7972739 | 0.79 | MAPT (0.43) | SIGMAR1DRD4PRKDCALDH1A1MAPT | |
| SCHEMBL28097291 | 0.73 | PRKDC (0.41) | TMEM97SIGMAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL24659191 | 0.71 | LMNA (0.41) | LMNASLC6A2SLC6A4SLC6A3PKM | |
| SCHEMBL6536567 | 0.70 | PARP1 (0.34) | TSHR | |
| SCHEMBL7729865 | 0.66 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL3948094 | 0.65 | LMNA (0.95) | SIGMAR1LMNAKMOPKMTSHR | |
| SCHEMBL254812 | 0.65 | LMNA (0.95) | SIGMAR1LMNAKMOPKMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973761-A1 | RED COLOURING HYPERCHROMIC 3$i(H)-NAPHTHO 2,1-$i(b)]PYRANS | JAMES ROBINSON LIMITED (GB) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998045281-A1 | RED COLOURING HYPERCHROMIC 3H-NAPHTHO[2,1-b]PYRANS | JAMES ROBINSON LIMITED (GB) | 1998-10-15 | — | — | WO | disclosed |