Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972739 | 0.89 | MAPT (0.43) | MAPTL3MBTL1RAB9AAKR1C3KMT2A | |
| SCHEMBL8107555 | 0.86 | TMEM97 (0.43) | MAPTRAB9ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6687407 | 0.84 | TMEM97 (0.44) | MAPTRAB9ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5158515 | 0.82 | TMEM97 (0.42) | MAPTSLC6A2SLC6A4SLC6A3PRKDC | |
| SCHEMBL7967548 | 0.79 | MAPT (0.41) | MAPTL3MBTL1RAB9AAKR1C3SLC6A2 | |
| SCHEMBL28097254 | 0.78 | AKR1C3 (0.44) | MAPTL3MBTL1RAB9AAKR1C3SLC6A2 | |
| SCHEMBL9032769 | 0.76 | RAB9A (0.43) | MAPTL3MBTL1RAB9AAKR1C3SLC6A2 | |
| SCHEMBL2208450 | 0.74 | AKR1C3 (0.68) | MAPTL3MBTL1RAB9AAKR1C3KMT2A | |
| SCHEMBL4349056 | 0.72 | AKR1C3 (0.66) | MAPTL3MBTL1RAB9AAKR1C3KMT2A | |
| Nitrogen SCHEMBL7794313 | 0.70 | AKR1C3 (0.62) | MAPTL3MBTL1RAB9AAKR1C3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050276767-A1 | Composition containing an oily phase and a naphthopyran dye, cosmetic treatment processes | L'OREAL (FR) | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050276767-A1 | Composition containing an oily phase and a naphthopyran dye, cosmetic treatment processes | CUTA, TYR, TPSD1 | MAPT 3880/4885L3MBTL1 4521/4885RAB9A 3804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.