SCHEMBL8107596

SCHEMBL8107596

CCC(=O)Nc1[c]cc(S(=O)(=O)O)c(N)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.39
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA9 Q16790 2/20 0.37
CA12 O43570 1/20 0.37
RAB9A P51151 4/20 0.34
GAA P10253 2/20 0.34
CTDSP1 Q9GZU7 1/20 0.33
POLB P06746 4/20 0.33
KMT2A Q03164 3/20 0.33
MAPT P10636 3/20 0.32
ALDH1A1 P00352 3/20 0.32
CYP3A4 P08684 2/20 0.32
MEN1 O00255 2/20 0.32
CA4 P22748 1/20 0.32
NPC1 O15118 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7894700 0.84 NPC1 (0.38) CA1CA2CA9CA12ALDH1A1
SCHEMBL8091760 0.82 NT5E (0.35) ALDH1A1TDP1HSD17B10
SCHEMBL8911715 0.75 MEN1 (0.41) ATMCA1CA2CA9CA12
SCHEMBL10384592 0.74 CA12 (0.53) ATMCA1CA2CA9CA12
SCHEMBL8912707 0.71 CTDSP1 (0.56) ATMCA1CA2CA9CA12
SCHEMBL4409480 0.69 TTR (0.37) CA1CA2CA9CA12RAB9A
SCHEMBL2214202 0.69 TTR (0.37) CA1CA2CA9CA12RAB9A
SCHEMBL11581837 0.68 ENPP2 (0.37) ALDH1A1LMNANPSR1HPGDHIF1A
SCHEMBL28754366 0.66 CA12 (0.37) CA1CA2CA9CA12ALDH1A1
SCHEMBL8091297 0.66 ALDH1A1 (0.31) ALDH1A1TDP1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0992546-A1 Mixtures of water soluble reactive azo dyes, process to manufacture them and their use DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2000-04-12 EP disclosed