Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.81 |
| ▸ | HPGD | P15428 | 5/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.81 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8124639 | 0.93 | KDM4E (0.68) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL551105 | 0.90 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL29353299 | 0.90 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL8115471 | 0.87 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL29450082 | 0.85 | ALDH1A1 (0.84) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL164671 | 0.85 | ALDH1A1 (0.84) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL8126323 | 0.83 | ALDH1A1 (0.88) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL8117517 | 0.82 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL10390227 | 0.81 | GRIN2D (0.62) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL8207252 | 0.81 | KDM4E (0.77) | KDM4EALDH1A1HPGDHSD17B10CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060602-A | Compounds for producing 2-naphthamide derivative | FUJIREBIO INC. (JP) | 2000-05-09 | — | — | US | disclosed |
| EP-0747369-B1 | Method of producing 2-naphthamide derivative, and compounds for producing 2-naphthamide derivative | FUJIREBIO KK (JP) | 2000-05-03 | — | — | EP | disclosed |
| US-5917046-A | Method for producing 2-naphthamide derivative, and compounds for producing 2-naphthamide derivative | FUJIREBIO INC. (JP) | 1999-06-29 | — | — | US | disclosed |
| US-5714613-A | Method of producing 2-naphthamide derivative, and compounds for producing 2-naphthamide derivative | FUJIREBIO INC. (JP) | 1998-02-03 | — | — | US | disclosed |
| EP-0747369-A1 | Method of producing 2-naphthamide derivative, and compounds for producing 2-naphthamide derivative | FUJIREBIO Inc. (JP) | 1996-12-11 | — | — | EP | disclosed |