Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 3/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6961356 | 0.83 | PRKDC (0.53) | ALDH1A1TSHRMAPK1TNKSESR1 | |
| SCHEMBL8107735 | 0.81 | CSNK2A2 (0.54) | TNKSESR1ESR2MAOBMIF | |
| SCHEMBL6172775 | 0.81 | SMN1; SMN2 (0.54) | ALDH1A1TSHRMAPK1POLBTNKS | |
| SCHEMBL8115383 | 0.81 | CSNK2A2 (0.57) | ALDH1A1TSHRMAOBMEN1KMT2A | |
| SCHEMBL29369936 | 0.78 | CYP3A4 (0.50) | ALDH1A1TSHRMAPK1POLBTNKS | |
| SCHEMBL8121356 | 0.77 | QPCT (0.59) | ALDH1A1TSHRMAPK1POLBTNKS | |
| SCHEMBL6824256 | 0.77 | AR (0.54) | ALDH1A1TSHRMAPK1TNKSESR1 | |
| SCHEMBL6829505 | 0.77 | EGFR (0.62) | ALDH1A1TSHRMAPK1POLBTNKS | |
| SCHEMBL28384631 | 0.75 | ALDH1A1 (0.56) | ALDH1A1TSHRMAPK1POLBTNKS | |
| SCHEMBL28384841 | 0.75 | ALDH1A1 (0.56) | ALDH1A1TSHRMAPK1POLBTNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| CN-1236357-A | Aminomethylene derivatives and ultraviolet absorber comprising the same | CHEMIPRO KASEI KAISHA LTD (JP) | 1999-11-24 | — | — | CN | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |