SCHEMBL8107735

SCHEMBL8107735

Cc1ccc(-c2cc(O)cc(=O)o2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 4/20 0.54
CSNK2B P67870 4/20 0.54
CSNK2A1 P68400 4/20 0.54
MEN1 O00255 1/20 0.52
GLA P06280 1/20 0.52
CYP3A4 P08684 1/20 0.52
KMT2A Q03164 1/20 0.52
CA12 O43570 2/20 0.50
CA9 Q16790 2/20 0.50
AR P10275 1/20 0.50
MAOB P27338 4/20 0.46
TNKS O95271 1/20 0.46
PARP1 P09874 1/20 0.46
TNKS2 Q9H2K2 1/20 0.46
PARP2 Q9UGN5 1/20 0.46
ELAVL1 Q15717 1/20 0.46
CCNC P24863 1/20 0.44
CDK8 P49336 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
ESR1 P03372 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6961356 0.83 PRKDC (0.53) CSNK2A2CSNK2BCSNK2A1MEN1GLA
SCHEMBL11852569 0.82 CSNK2A2 (0.53) CSNK2A2CSNK2BCSNK2A1KMT2ACA12
SCHEMBL8107763 0.81 ALDH1A1 (0.55) CSNK2A2CSNK2BCSNK2A1MEN1GLA
SCHEMBL6172775 0.81 SMN1; SMN2 (0.54) CSNK2A2CSNK2BCSNK2A1MEN1GLA
SCHEMBL6829505 0.81 EGFR (0.62) CSNK2A2CSNK2BCSNK2A1MEN1CYP3A4
SCHEMBL8121356 0.81 QPCT (0.59) CSNK2A2CSNK2BCSNK2A1MEN1GLA
SCHEMBL8116989 0.81 QPCT (0.59) CSNK2A2CSNK2BCSNK2A1MEN1GLA
SCHEMBL29369936 0.78 CYP3A4 (0.50) CSNK2A2CSNK2BCSNK2A1MEN1GLA
SCHEMBL6824256 0.77 AR (0.54) CSNK2A2CSNK2BCSNK2A1MEN1GLA
SCHEMBL6965252 0.77 TNKS (0.58) CYP3A4CA12CA9TNKSESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6114546-A Aminomethylene derivatives and ultraviolet absorbent comprising thereof CHEMIPRO KASEI KAISHA, LIMITED (JP) 2000-09-05 US disclosed
CN-1236357-A Aminomethylene derivatives and ultraviolet absorber comprising the same CHEMIPRO KASEI KAISHA LTD (JP) 1999-11-24 CN disclosed
EP-0950655-A1 AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME CHEMIPRO KASEI KAISHA, LIMITED (JP) 1999-10-20 EP disclosed