Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | NEK2 | P51955 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6571965 | 0.87 | CHEK1 (0.48) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL6574447 | 0.87 | ALDH1A1 (0.41) | DYRK1ANPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL8107883 | 0.75 | MAPK1 (0.36) | NPC1ALDH1A1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL6570988 | 0.74 | ALDH1A1 (0.46) | DYRK1ANPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL3790652 | 0.74 | ALDH1A1 (0.48) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| Hydrochloric Acid SCHEMBL6571889 | 0.72 | ALDH1A1 (0.44) | NPC1ALDH1A1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL27735945 | 0.72 | DPP4 (0.50) | NPC1ALDH1A1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL3792075 | 0.71 | ALDH1A1 (0.59) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL3786502 | 0.71 | ALDH1A1 (0.48) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL1201130 | 0.70 | LIPG (0.45) | ALDH1A1TP53CYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-A2 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | Wella Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999059527-A2 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 1999-11-25 | — | — | WO | disclosed |