Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 7/20 | 0.44 |
| ▸ | FNTA | P49354 | 6/20 | 0.39 |
| ▸ | FNTB | P49356 | 6/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.39 |
| ▸ | FPR1 | P21462 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449160 | 0.90 | ITGB3 (0.59) | ITGB3ITGA2BHDAC1HDAC8HDAC6 | |
| SCHEMBL7447587 | 0.89 | ITGB3 (0.59) | ITGB3ITGA2BHDAC1HDAC8HDAC6 | |
| SCHEMBL7420718 | 0.88 | ITGB3 (0.72) | ITGB3ITGA2BHDAC1HDAC8HDAC6 | |
| SCHEMBL7415603 | 0.88 | ITGB3 (0.72) | ITGB3ITGA2BHDAC1HDAC8HDAC6 | |
| SCHEMBL8102018 | 0.87 | ITGB3 (0.56) | ITGB3ITGA2BHDAC1HDAC8HDAC6 | |
| SCHEMBL7442381 | 0.86 | ITGB3 (0.62) | ITGB3ITGA2BHDAC1HDAC8HDAC6 | |
| SCHEMBL7449777 | 0.85 | ITGB3 (0.59) | ITGB3ITGA2BHDAC1HDAC8HDAC6 | |
| SCHEMBL7453824 | 0.84 | ITGB3 (0.60) | ITGB3ITGA2BHDAC1HDAC8HDAC6 | |
| SCHEMBL7455673 | 0.84 | ITGB3 (0.53) | ITGB3ITGA2BHDAC1HDAC8HDAC6 | |
| SCHEMBL7448793 | 0.84 | ITGB3 (0.78) | ITGB3ITGA2BFPR2FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025358-A | Double prodrugs of potent GP IIb/IIIa antagonists | G. D. SEARLE & CO. (US) | 2000-02-15 | — | — | US | disclosed |