Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.55 |
| ▸ | ITGAV | P06756 | 5/20 | 0.45 |
| ▸ | CTSK | P43235 | 7/20 | 0.42 |
| ▸ | CTSB | P07858 | 4/20 | 0.42 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | PLG | P00747 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | PLAT | P00750 | 2/20 | 0.42 |
| ▸ | KLK8 | O60259 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | KLK4 | Q9Y5K2 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8107961 | 1.00 | ITGB3 (0.55) | ITGB3ITGA2BITGAVCTSKCTSB | |
| Trifluoroacetic Acid SCHEMBL8123138 | 0.96 | ITGB3 (0.54) | ITGB3ITGA2BITGAVCTSKCTSB | |
| Trifluoroacetic Acid SCHEMBL8123141 | 0.96 | ITGB3 (0.54) | ITGB3ITGA2BITGAVCTSKCTSB | |
| SCHEMBL8116534 | 0.92 | ITGB3 (0.61) | ITGB3ITGA2BCTSKCTSBCTSS | |
| SCHEMBL8116529 | 0.92 | ITGB3 (0.61) | ITGB3ITGA2BCTSKCTSBCTSS | |
| SCHEMBL8123145 | 0.90 | ITGB3 (0.50) | ITGB3ITGA2BCTSKCTSBCTSS | |
| SCHEMBL7421587 | 0.86 | ITGB3 (0.56) | ITGB3ITGA2BITGAV | |
| SCHEMBL8109889 | 0.86 | ITGB3 (0.45) | ITGB3ITGA2BITGAVCTSKCTSB | |
| Trifluoroacetic Acid SCHEMBL8123151 | 0.83 | ITGB3 (0.44) | ITGB3ITGA2BITGAVCTSKCTSB | |
| SCHEMBL9029468 | 0.79 | ITGB3 (0.48) | ITGB3ITGA2BF2PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691953-B1 | 1-AMIDINOPHENYL-PYRROLIDONES/ PIPERIDINONES AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2000-08-02 | — | — | EP | claimed |