Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.48 |
| ▸ | PLG | P00747 | 5/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.39 |
| ▸ | PROC | P04070 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.38 |
| ▸ | PLAU | P00749 | 3/20 | 0.38 |
| ▸ | PLAT | P00750 | 3/20 | 0.38 |
| ▸ | KLK8 | O60259 | 2/20 | 0.38 |
| ▸ | KLK4 | Q9Y5K2 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
| ▸ | KLK2 | P20151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8123145 | 0.86 | ITGB3 (0.50) | ITGB3ITGA2BPLGKLKB1PROC | |
| SCHEMBL7424541 | 0.84 | ITGB3 (0.51) | ITGB3ITGA2BF10F2 | |
| SCHEMBL7422015 | 0.82 | ITGB3 (0.56) | ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL8123138 | 0.82 | ITGB3 (0.54) | ITGB3ITGA2BPLGKLKB1PROC | |
| Trifluoroacetic Acid SCHEMBL8123141 | 0.82 | ITGB3 (0.54) | ITGB3ITGA2BPLGKLKB1PROC | |
| Trifluoroacetic Acid SCHEMBL8124196 | 0.79 | ITGB3 (0.54) | ITGB3ITGA2BPLGKLKB1PROC | |
| SCHEMBL8107970 | 0.79 | ITGB3 (0.55) | ITGB3ITGA2BPLGF10F2 | |
| SCHEMBL8107961 | 0.79 | ITGB3 (0.55) | ITGB3ITGA2BPLGF10F2 | |
| SCHEMBL7411805 | 0.77 | ITGB3 (0.73) | ITGB3ITGA2B | |
| SCHEMBL7448817 | 0.77 | ITGB3 (0.73) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691953-A1 | 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1996-01-17 | — | — | EP | claimed |