SCHEMBL810801

SCHEMBL810801

CCOC(C)Oc1ccc(C(C)=O)cc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.50
RAB9A P51151 2/20 0.50
HPGD P15428 2/20 0.50
POLB P06746 2/20 0.49
NPSR1 Q6W5P4 2/20 0.49
LMNA P02545 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
PPARG P37231 1/20 0.48
PPARA Q07869 1/20 0.48
GAA P10253 1/20 0.47
KMT2A Q03164 2/20 0.44
PARP10 Q53GL7 1/20 0.43
MAOB P27338 5/20 0.42
STS P08842 1/20 0.42
ALDH1A1 P00352 1/20 0.41
MAOA P21397 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11145345 0.86 KMT2A (0.62) MAPTKMT2APARP10ALDH1A1
Hydrochloric Acid SCHEMBL11155443 0.85 KMT2A (0.61) MAPTKMT2APARP10ALDH1A1
SCHEMBL14609920 0.85 ABCB1 (0.47) MAPTRAB9AHPGDL3MBTL1GAA
SCHEMBL11145332 0.85 KMT2A (0.43) MAPTHPGDPOLBNPSR1LMNA
SCHEMBL19203888 0.85 MAPT (0.51) MAPTRAB9AHPGDPOLBNPSR1
SCHEMBL19117541 0.83 SMN1; SMN2 (0.55) MAPTRAB9AHPGDNPSR1GAA
4-(Acetate)Acetophenone SCHEMBL9065455 0.83 ELANE (0.49) MAPTRAB9AHPGDPOLBNPSR1
SCHEMBL3852488 0.83 LMNA (0.52) POLBLMNAL3MBTL1PPARAKMT2A
SCHEMBL685750 0.83 KMT2A (0.37) MAPTHPGDPOLBNPSR1LMNA
SCHEMBL4460034 0.82 KMT2A (0.41) MAPTRAB9AHPGDPOLBNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10915022-B2 Photoresist composition and process for producing photoresist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-02-09 US disclosed
US-20110178314-A1 PROCESS FOR PREPARING 2-ALKYL-3-AROYL-5-NITRO-BENZOFURANS LONZA AG (CH) 2011-07-21 US disclosed
EP-2344467-A1 PROCESS FOR PREPARING 2-ALKYL-3-AROYL-5-NITRO-BENZOFURANS Lonza Ltd. (CH) 2011-07-20 EP disclosed
EP-2246341-A1 Process for preparing 2-Alkyl-3-aroyl-5-nitro-benzofurans Lonza Ltd. (CH) 2010-11-03 EP disclosed
WO-2010040261-A1 PROCESS FOR PREPARING 2-ALKYL-3-AROYL-5-NITRO-BENZOFURANS LONZA LTD (CH) 2010-04-15 WO disclosed
US-5053507-A Liquid crystal dopants ARAKAWA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1991-10-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110178314-A1 PROCESS FOR PREPARING 2-ALKYL-3-AROYL-5-NITRO-BENZOFURANS NR4A3, CBR3, NR4A1 MAPT 4885/4885RAB9A 3180/4885HPGD 2354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.