Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | CTSG | P08311 | 2/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8093156 | 0.99 | PTPN1 (0.46) | PTPN1TDP2PAX8HKDC1TLR9 | |
| SCHEMBL8092990 | 0.95 | TDP2 (0.44) | PTPN1TDP2PAX8HKDC1TLR9 | |
| SCHEMBL8102495 | 0.89 | TDP2 (0.46) | TDP2PAX8HKDC1TLR9MAPT | |
| SCHEMBL8092562 | 0.88 | MAPT (0.45) | PTPN1TDP2PAX8HKDC1TLR9 | |
| SCHEMBL8092958 | 0.86 | HSP90AA1 (0.52) | PTPN1TDP2PAX8HKDC1TLR9 | |
| SCHEMBL8102913 | 0.85 | DHODH (0.43) | TDP2PAX8HKDC1TLR9MAPT | |
| SCHEMBL8100694 | 0.85 | RAB9A (0.52) | PTPN1TDP2PAX8HKDC1TLR9 | |
| SCHEMBL8100385 | 0.85 | MAPT (0.50) | TDP2PAX8HKDC1TLR9MAPT | |
| SCHEMBL8108866 | 0.85 | HSP90AA1 (0.54) | PTPN1TDP2PAX8HKDC1TLR9 | |
| SCHEMBL8100889 | 0.84 | TDP2 (0.61) | PTPN1TDP2PAX8HKDC1TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013674-A | INDENONE AMIDE DERIVATIVES, USEFUL FOR FOR THE INHIBITION OF LEUKOCYTE ADHERENCE TO ENDOTHELIAL CELLS; USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES, AS ARTHRITIS, ASTHAMA, PSORIASIS, RESPIRATORY DISTRESS SYNDROME, STROKE AND ULCER | ELI LILLY AND COMPANY (US) | 2000-01-11 | — | — | US | disclosed |
| EP-0882706-A1 | Cell adhesion inhibitors | ELI LILLY AND COMPANY (US) | 1998-12-09 | — | — | EP | disclosed |