Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 5/20 | 0.43 |
| ▸ | NAAA | Q02083 | 4/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8108442 | 0.80 | MAPT (0.44) | MAPTRXFP1ALOX5HDAC1HDAC2 | |
| SCHEMBL8094797 | 0.80 | MAPT (0.44) | MAPTRXFP1ALOX5HDAC1HDAC2 | |
| SCHEMBL8094804 | 0.77 | POLB (0.43) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8104160 | 0.74 | HDAC3 (0.42) | HDAC1HDAC2MEN1NPC1RAB9A | |
| SCHEMBL11137519 | 0.72 | MAPT (0.77) | MAPTRXFP1ALOX5HDAC1HDAC2 | |
| SCHEMBL1508071 | 0.72 | MAPT (0.77) | MAPTRXFP1ALOX5HDAC1HDAC2 | |
| SCHEMBL28609434 | 0.72 | MAPT (0.77) | MAPTRXFP1ALOX5HDAC1HDAC2 | |
| SCHEMBL7005662 | 0.70 | MAPT (0.59) | MAPTRXFP1ALOX5HDAC1HDAC2 | |
| SCHEMBL4886613 | 0.70 | MAPT (0.73) | MAPTRXFP1ALOX5HDAC1HDAC2 | |
| SCHEMBL17002040 | 0.69 | MAPT (0.67) | MAPTRXFP1ALOX5HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6071899-A | Azetidinone derivatives for the treatment of atherosclerosis | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-06-06 | — | — | US | disclosed |