Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104145 | 0.81 | HPGD (0.40) | POLBHPGDACEHMOX1HDAC3 | |
| SCHEMBL8108482 | 0.77 | MAPT (0.46) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8108430 | 0.76 | HMOX1 (0.40) | POLBHPGDABL1RIN1ACE | |
| SCHEMBL5681564 | 0.70 | HPGD (0.59) | HPGDMEN1KMT2AHDAC3 | |
| SCHEMBL30874195 | 0.70 | HPGD (0.59) | HPGDMEN1KMT2AHDAC3 | |
| SCHEMBL932750 | 0.70 | HPGD (0.59) | HPGDMEN1KMT2AHDAC3 | |
| SCHEMBL8165390 | 0.70 | HPGD (0.59) | HPGDMEN1KMT2AHDAC3 | |
| SCHEMBL4392253 | 0.70 | HPGD (0.59) | HPGDMEN1KMT2AHDAC3 | |
| SCHEMBL4636973 | 0.70 | OPRD1 (0.42) | ABL1RIN1 | |
| SCHEMBL8443320 | 0.70 | ACE (0.42) | POLBACEHMOX1NPC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6071899-A | Azetidinone derivatives for the treatment of atherosclerosis | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-06-06 | — | — | US | disclosed |