Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9423891 | 0.87 | HSD17B10 (0.38) | ESR1ESR2HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL8113342 | 0.83 | ESR1 (0.53) | ESR1ESR2HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL4471833 | 0.79 | ESR1 (0.49) | ESR1ESR2CYP3A4ALDH1A1RXFP1 | |
| SCHEMBL4460177 | 0.78 | ESR1 (0.55) | ESR1ESR2HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL4465968 | 0.77 | ESR1 (0.46) | ESR1ESR2CYP3A4ALDH1A1HTT | |
| SCHEMBL4463750 | 0.75 | ESR1 (0.45) | ESR1ESR2ALDH1A1CYP2C9 | |
| SCHEMBL1448894 | 0.75 | ESR1 (0.60) | ESR1ESR2HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL29599541 | 0.75 | ESR1 (0.60) | ESR1ESR2HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL4457785 | 0.74 | ESR1 (0.50) | ESR1ESR2HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL4457796 | 0.74 | ESR1 (0.58) | ESR1ESR2HSD17B1HSD17B2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028161-A | EXCELLENT TRANSPARENCY, HEAT RESISTANCE AND MECHANICAL PROPERTIES AND A LOW BIREFRINGENCE, MELT FLUIDITY AND MOLDABILITY; AN OPTICAL DISK, LENS AND AN OPTICAL FIBER | MITSUI CHEMICALS, INC. (JP) | 2000-02-22 | — | — | US | disclosed |
| EP-0926180-A2 | A polycarbonate copolymer and applications thereof | Mitsui Chemicals, Inc. (JP) | 1999-06-30 | — | — | EP | disclosed |