SCHEMBL4471833

SCHEMBL4471833

CCOc1cc(O)ccc1C(C)(C)c1cccc(C(C)(C)c2ccc(O)cc2OCC)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.49
ESR2 Q92731 3/20 0.49
CALM1 P0DP23 1/20 0.40
RXFP1 Q9HBX9 2/20 0.37
L3MBTL1 Q9Y468 3/20 0.37
ALDH1A1 P00352 5/20 0.36
CYP3A4 P08684 1/20 0.36
CDK5 Q00535 1/20 0.36
CDK5R1 Q15078 1/20 0.36
MEN1 O00255 4/20 0.35
KMT2A Q03164 4/20 0.35
MAPT P10636 4/20 0.35
GAA P10253 3/20 0.35
THRB P10828 2/20 0.35
RECQL P46063 1/20 0.35
BLM P54132 1/20 0.35
ATM Q13315 1/20 0.35
PLEC Q15149 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CAPN1 P07384 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4467564 0.89 ESR1 (0.44) ESR1ESR2CALM1L3MBTL1ALDH1A1
SCHEMBL4465968 0.88 ESR1 (0.46) ESR1ESR2L3MBTL1ALDH1A1CYP3A4
SCHEMBL6059481 0.87 LTA4H (0.40) ESR1ESR2CALM1L3MBTL1ALDH1A1
SCHEMBL4463750 0.87 ESR1 (0.45) ESR1ESR2L3MBTL1ALDH1A1MEN1
SCHEMBL8113342 0.83 ESR1 (0.53) ESR1ESR2ALDH1A1CYP3A4MEN1
SCHEMBL11680067 0.80 ALDH1A1 (0.47) ESR1ESR2CALM1L3MBTL1ALDH1A1
SCHEMBL8108512 0.79 ESR1 (0.49) ESR1ESR2RXFP1ALDH1A1CYP3A4
SCHEMBL4465516 0.76 ESR1 (0.53) ESR1ESR2ALDH1A1CYP3A4HSD17B10
SCHEMBL1448894 0.75 ESR1 (0.60) ESR1ESR2ALDH1A1CYP3A4MAPT
SCHEMBL29599541 0.75 ESR1 (0.60) ESR1ESR2ALDH1A1CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582355-B2 Optical unit using plastic lenses FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-20060046065-A1 Optical unit using plastic lenses FUJI PHOTO FILM CO., LTD. 2006-03-02 US disclosed