Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | AGER | Q15109 | 1/20 | 0.52 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11819987 | 0.85 | GAA (0.48) | SMN1; SMN2LMNATSHRHTTMAPT | |
| SCHEMBL8104220 | 0.83 | GAA (0.47) | SMN1; SMN2LMNATSHRHTTMAPT | |
| SCHEMBL8094851 | 0.80 | KDM4E (0.47) | SMN1; SMN2LMNATSHRHTTMAPT | |
| SCHEMBL8104229 | 0.80 | ALDH1A1 (0.42) | SMN1; SMN2LMNATSHRHTTMAPT | |
| SCHEMBL17993868 | 0.78 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNATSHRHTTMAPT | |
| SCHEMBL1022300 | 0.77 | TLR8 (0.69) | SMN1; SMN2LMNATSHRHTTGAA | |
| SCHEMBL7786135 | 0.76 | PTGDR2 (0.47) | SMN1; SMN2LMNATSHRMAPTKDM4E | |
| SCHEMBL2580465 | 0.76 | ALDH1A1 (0.46) | SMN1; SMN2LMNATSHRMAPTKDM4E | |
| SCHEMBL1979951 | 0.76 | BACE1 (0.49) | TSHRMAPTKDM4EALDH1A1GAA | |
| SCHEMBL29666216 | 0.76 | BACE1 (0.49) | TSHRMAPTKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6037473-A | AS SUNSCREENS IN COSMETIC AND PHARMACEUTICAL PREPARATIONS; FOR ENHANCING PHOTOSTABILITY OF INDUSTRIAL PRODUCTS SUCH AS PAINTS, VARNISHES, PLASTICS, TEXTILES, PACKAGING MATERIALS AND RUBBERS | HAARMANN & REIMER GMBH (DE) | 2000-03-14 | — | — | US | disclosed |
| US-5961960-A | Use of substituted benzazoles as UV absorbers, new benzazoles and processes for their preparation | HAARMANN & REIMER GMBH (DE) | 1999-10-05 | — | — | US | disclosed |
| EP-0843995-A2 | Use of substituted benzazoles as UV absorbents, new benzazoles and their preparation | HAARMANN & REIMER GMBH (DE) | 1998-05-27 | — | — | EP | disclosed |