Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 16/20 | 0.39 |
| ▸ | FPR1 | P21462 | 9/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8109546 | 0.89 | ITGB3 (0.41) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| Acetic Acid SCHEMBL9095800 | 0.86 | ITGB3 (0.43) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL8117806 | 0.84 | HTT (0.31) | ITGB3ITGA2B | |
| SCHEMBL8116006 | 0.84 | ITGB3 (0.42) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL8108531 | 0.83 | ITGB3 (0.58) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL8122590 | 0.83 | ITGB3 (0.47) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL7530926 | 0.81 | ITGB3 (0.51) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL8125482 | 0.81 | ITGB3 (0.33) | ITGB3ITGA2B | |
| SCHEMBL8118294 | 0.81 | ITGB3 (0.33) | ITGB3ITGA2B | |
| Acetic Acid SCHEMBL7414165 | 0.81 | ITGB3 (0.49) | ITGB3ITGA2BFPR2FPR1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691953-B1 | 1-AMIDINOPHENYL-PYRROLIDONES/ PIPERIDINONES AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2000-08-02 | — | — | EP | claimed |