Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8118294 | 1.00 | ITGB3 (0.33) | ITGB3ITGA2BAVPR2AVPR1ACYP1A2 | |
| SCHEMBL8117806 | 0.95 | HTT (0.31) | ITGB3ITGA2BHTT | |
| SCHEMBL8118631 | 0.89 | CYP1A2 (0.35) | ITGB3ITGA2BAVPR2AVPR1ACYP1A2 | |
| SCHEMBL8115483 | 0.89 | ITGB3 (0.32) | ITGB3ITGA2B | |
| SCHEMBL8107039 | 0.89 | ITGB3 (0.40) | ITGB3ITGA2B | |
| SCHEMBL8121584 | 0.89 | ITGB3 (0.40) | ITGB3ITGA2B | |
| SCHEMBL7424236 | 0.88 | ITGB3 (0.36) | ITGB3ITGA2BAVPR2AVPR1AHSD17B10 | |
| SCHEMBL7424245 | 0.88 | ITGB3 (0.36) | ITGB3ITGA2BAVPR2AVPR1AHSD17B10 | |
| SCHEMBL8108831 | 0.86 | ITGB3 (0.35) | ITGB3ITGA2B | |
| SCHEMBL7532349 | 0.85 | UGCG (0.36) | KDM4ERAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691953-B1 | 1-AMIDINOPHENYL-PYRROLIDONES/ PIPERIDINONES AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2000-08-02 | — | — | EP | claimed |