Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.79 |
| ▸ | F3 | P13726 | 1/20 | 0.79 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.79 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.79 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.79 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.79 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.79 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.79 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | APP | P05067 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.58 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.58 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.54 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.53 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.49 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Niacinamide SCHEMBL5299370 | 0.91 | F7 (0.96) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL29150592 | 0.91 | F7 (0.96) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL675207 | 0.91 | F7 (0.96) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL28768072 | 0.89 | F7 (0.79) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL460466 | 0.89 | F7 (1.00) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL29624874 | 0.89 | — | — | |
| Niacinamide SCHEMBL19978192 | 0.89 | — | — | |
| Niacinamide SCHEMBL2926 | 0.89 | — | — | |
| Niacinamide SCHEMBL28510235 | 0.88 | F7 (0.76) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL7752277 | 0.88 | F7 (0.76) | F7F3SARM1SIRT2SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170360687-A1 | SUBSTRATE-BASED PRODUCT, ITS METHOD OF PREPARATION AND COSMETIC USES THEREOF | L'OREAL (FR) | 2017-12-21 | — | — | US | claimed |
| EP-3236922-A1 | SUBSTRATE-BASED PRODUCT, ITS METHOD OF PREPARATION AND COSMETIC USES THEREOF | L'OREAL (FR) | 2017-11-01 | — | — | EP | claimed |
| WO-2016102702-A1 | SUBSTRATE-BASED PRODUCT, ITS METHOD OF PREPARATION AND COSMETIC USES THEREOF | L'OREAL (FR) | 2016-06-30 | — | — | WO | claimed |
| US-20060147508-A1 | Concurrent Enhancement of Skin Penetration of Organic Base Active Agents and Organic Hydroxy Acid Active Agents as Their Ion-Pair Complexes | BIODERM RESEARCH (US) | 2006-07-06 | — | — | US | claimed |
| US-20040228884-A1 | Ion-pair delivery system for cosmetic and pharmaceutical compositions | GUPTA SHYAM K (US) | 2004-11-18 | — | — | US | claimed |
| US-20040156873-A1 | Topically Bioavailable Acne and Rosacea Treatment Compositions | GUPTA SHYAM K (US) | 2004-08-12 | — | — | US | claimed |
| US-20040092482-A1 | Hydroxy acids based delivery systems for skin resurfacing and anti-aging compositions | GUPTA SHYAM K (US) | 2004-05-13 | — | — | US | claimed |
| US-20040081672-A1 | Niacinamide, niacin, and niacin esters based delivery systems for treating topical disorders of skin and skin aging | GUPTA SHYAM K (US) | 2004-04-29 | — | — | US | claimed |
| WO-2025082655-A1 | LOW WATER CONTENT W/O EMULSION COMPRISING A HYDROPHOBIC FILM-FORMING POLYMER, A LINEAR SILICONE POLYOL, HYALURONIC ACID, A VITAMIN B3 AND A XANTHINE BASE | L'OREAL (FR) | 2025-04-24 | — | — | WO | disclosed |
| US-20250099363-A1 | COSMETIC WATER-IN-OIL EMULSION COMPRISING A SPECIFIC WATER-SOLUBLE UV SCREENING AGENT, A BASE, A VOLATILE OIL, A HYDROPHOBIC FILM-FORMING POLYMER, A POLYOXYALKYLENATED LINEAR POLYDIMETHYLMETHYLSILOXANE AND A VITAMIN B3 | L'OREAL (FR) | 2025-03-27 | — | — | US | disclosed |
| US-20240350394-A1 | A NON-THERAPEUTIC COSMETIC METHOD FOR REDUCING WRINKLES ON A SKIN SURFACE | L'OREAL (FR) | 2024-10-24 | — | — | US | disclosed |
| EP-4436535-A1 | COSMETIC WATER-IN-OIL EMULSION COMPRISING A SPECIFIC WATER-SOLUBLE UV SCREENING AGENT, A BASE, A VOLATILE OIL, A HYDROPHOBIC FILM-FORMING POLYMER, A POLYOXYALKYLENATED LINEAR POLYDIMETHYLMETHYLSILOXANE AND A VITAMIN B3 | L'OREAL (FR) | 2024-10-02 | — | — | EP | disclosed |
| CN-118302145-A | Cosmetic water-in-oil emulsion comprising a specific water-soluble UV screening agent, a base, a volatile oil, a hydrophobic film-forming polymer, a polyoxyalkylene-alkylated linear polydimethylsiloxane and vitamin B3 | 莱雅公司 | 2024-07-05 | — | — | CN | disclosed |
| EP-4370092-A2 | A NON-THERAPEUTIC COSMETIC METHOD FOR REDUCING WRINKLES ON A SKIN SURFACE | L'OREAL (FR) | 2024-05-22 | — | — | EP | disclosed |
| US-20060039887-A1 | Cosmetic or pharmaceutical composition for skin care | INFINITY2 HEALTH SCIENCES, INC. | 2006-02-23 | — | — | US | disclosed |
| WO-2005123101-A1 | BLACKBERRY EXTRACT | SYMRISE GMBH & CO. KG (DE) | 2005-12-29 | — | — | WO | disclosed |
| US-20050037038-A1 | Cosmetic Dermabrasion Treatment System | GUPTA SHYAM K (US) | 2005-02-17 | — | — | US | disclosed |
| US-20040228884-A1 | Ion-pair delivery system for cosmetic and pharmaceutical compositions | GUPTA SHYAM K (US) | 2004-11-18 | — | — | US | disclosed |
| US-20040092482-A1 | Hydroxy acids based delivery systems for skin resurfacing and anti-aging compositions | GUPTA SHYAM K (US) | 2004-05-13 | — | — | US | disclosed |
| US-20040081672-A1 | Niacinamide, niacin, and niacin esters based delivery systems for treating topical disorders of skin and skin aging | GUPTA SHYAM K (US) | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092482-A1 | Hydroxy acids based delivery systems for skin resurfacing and anti-aging compositions | CUTA, HIRA, HARS1 | F7 3378/4885F3 4156/4885SARM1 4221/4885 |
| US-20250099363-A1 | COSMETIC WATER-IN-OIL EMULSION COMPRISING A SPECIFIC WATER-SOLUBLE UV SCREENING AGENT, A BASE, A VOLATILE OIL, A HYDROPHOBIC FILM-FORMING POLYMER, A POLYOXYALKYLENATED LINEAR POLYDIMETHYLMETHYLSILOXANE AND A VITAMIN B3 | KRT18, RARB, RXRB | F7 267/4885F3 1456/4885SARM1 2507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.