Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8108961 | 1.00 | ALDH1A1 (0.35) | ALDH1A1LMNADPP8DPP9HSD11B1 | |
| SCHEMBL8540343 | 0.94 | HSD11B1 (0.36) | ALDH1A1LMNADPP8DPP9HSD11B1 | |
| SCHEMBL8537617 | 0.94 | HSD11B1 (0.36) | ALDH1A1LMNADPP8DPP9HSD11B1 | |
| SCHEMBL8540340 | 0.94 | HSD11B1 (0.36) | ALDH1A1LMNADPP8DPP9HSD11B1 | |
| SCHEMBL8537616 | 0.94 | HSD11B1 (0.36) | ALDH1A1LMNADPP8DPP9HSD11B1 | |
| SCHEMBL8104555 | 0.84 | HSD11B1 (0.44) | ALDH1A1LMNADPP8DPP9HSD11B1 | |
| SCHEMBL8102742 | 0.84 | HSD11B1 (0.44) | ALDH1A1LMNADPP8DPP9HSD11B1 | |
| SCHEMBL8095391 | 0.84 | HSD11B1 (0.44) | ALDH1A1LMNADPP8DPP9HSD11B1 | |
| SCHEMBL8104700 | 0.84 | HSD11B1 (0.44) | ALDH1A1LMNADPP8DPP9HSD11B1 | |
| SCHEMBL8102654 | 0.83 | HSD11B1 (0.37) | ALDH1A1LMNADPP8DPP9HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090802-A | BACTERICIDE | SANKYO COMPANY, LIMITED (JP) | 2000-07-18 | — | — | US | disclosed |