Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 9/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22005187 | 0.86 | RAB9A (0.42) | ALDH1A1KDM4EGAAMAPTHTT | |
| SCHEMBL3451425 | 0.83 | CHKA (0.54) | CHKAALDH1A1KDM4EGAAMAPT | |
| SCHEMBL4577130 | 0.80 | TRIM24 (0.52) | CHKABCHEACHEALDH1A1KDM4E | |
| SCHEMBL12497577 | 0.78 | CHKA (0.47) | CHKABCHEACHEALDH1A1KDM4E | |
| SCHEMBL11850922 | 0.76 | TRIM24 (0.56) | CHKABCHEACHEALDH1A1KDM4E | |
| SCHEMBL2174173 | 0.75 | ALDH1A1 (0.67) | CHKAALDH1A1KDM4EGAAMAPT | |
| SCHEMBL11859247 | 0.74 | ALDH1A1 (0.57) | CHKABCHEACHEALDH1A1KDM4E | |
| SCHEMBL9915870 | 0.74 | CHKA (0.65) | CHKABCHEACHEALDH1A1KDM4E | |
| SCHEMBL4573969 | 0.72 | CHKA (0.50) | CHKABCHEACHEALDH1A1KDM4E | |
| SCHEMBL6641575 | 0.72 | CHKA (0.50) | CHKABCHEACHEALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973761-A1 | RED COLOURING HYPERCHROMIC 3$i(H)-NAPHTHO 2,1-$i(b)]PYRANS | JAMES ROBINSON LIMITED (GB) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998045281-A1 | RED COLOURING HYPERCHROMIC 3H-NAPHTHO[2,1-b]PYRANS | JAMES ROBINSON LIMITED (GB) | 1998-10-15 | — | — | WO | disclosed |