Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.51 |
| ▸ | HTR1A | P08908 | 6/20 | 0.49 |
| ▸ | HTR2C | P28335 | 4/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8870196 | 0.99 | SIGMAR1 (0.50) | SIGMAR1HTR1AHTR2CADRA2AADRA2B | |
| SCHEMBL8870657 | 0.91 | SIGMAR1 (0.54) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9437692 | 0.87 | SIGMAR1 (0.51) | SIGMAR1HTR1AHTR2CADRA2AADRA2B | |
| SCHEMBL8109725 | 0.87 | SIGMAR1 (0.53) | SIGMAR1HTR1AHTR2CADRA2AADRA2B | |
| SCHEMBL8110589 | 0.87 | SIGMAR1 (0.51) | SIGMAR1HTR1AHTR2CADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL8870580 | 0.86 | SIGMAR1 (0.52) | SIGMAR1HTR1AHTR2CADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL8870179 | 0.86 | SIGMAR1 (0.50) | SIGMAR1HTR1AHTR2CADRA2AADRA2B | |
| SCHEMBL9437747 | 0.85 | SIGMAR1 (0.49) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL8116630 | 0.83 | SIGMAR1 (0.58) | SIGMAR1HTR1AHTR2CADRA2AADRA2B | |
| SCHEMBL9437708 | 0.82 | SIGMAR1 (0.51) | SIGMAR1HTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673933-B1 | Aminoalkyl benzoxazolinones and benzothiazolinones process for their preparation and compositions containing them | ADIR (FR) | 2000-11-08 | — | — | EP | disclosed |
| US-5688811-A | PSYCHOLOGICAL DISORDERS; NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-11-18 | — | — | US | disclosed |
| EP-0673933-A1 | Aminoalkyl benzoxazolinones and benzothiazolinones process for their preparation and compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-27 | — | — | EP | disclosed |