Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.51 |
| ▸ | HTR1A | P08908 | 6/20 | 0.49 |
| ▸ | HTR2C | P28335 | 4/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437747 | 0.93 | SIGMAR1 (0.49) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9437770 | 0.91 | SIGMAR1 (0.54) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL8109064 | 0.87 | SIGMAR1 (0.51) | SIGMAR1HTR1AHTR2CADRA2AADRA2B | |
| SCHEMBL8110589 | 0.87 | SIGMAR1 (0.51) | SIGMAR1HTR1AHTR2CADRA2AADRA2B | |
| SCHEMBL8109725 | 0.87 | SIGMAR1 (0.53) | SIGMAR1HTR1AHTR2CADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL8870196 | 0.86 | SIGMAR1 (0.50) | SIGMAR1HTR1AHTR2CADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL8870580 | 0.86 | SIGMAR1 (0.52) | SIGMAR1HTR1AHTR2CADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL8870179 | 0.86 | SIGMAR1 (0.50) | SIGMAR1HTR1AHTR2CADRA2AADRA2B | |
| SCHEMBL8114236 | 0.85 | SIGMAR1 (0.59) | SIGMAR1HTR1AHTR2CADRA2AADRA2B | |
| SCHEMBL9437778 | 0.84 | SIGMAR1 (0.51) | SIGMAR1HTR1AHTR2CADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296477-A | Antidepressants | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |
| US-5268381-A | Antidepressant or anxiolytic compound | ADIR ET COMPAGNIE (FR) | 1993-12-07 | — | — | US | disclosed |
| US-5196434-A | Antidepressants, anxiolytic agents | ADIR ET COMPAGNIE (FR) | 1993-03-23 | — | — | US | disclosed |