Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8115931 | 0.78 | MAPT (0.36) | HAO1PLK1ALDH1A1 | |
| SCHEMBL10660683 | 0.77 | HAO1 (0.58) | HAO1PLK1TAS1R3TAS1R1MMP2 | |
| SCHEMBL19806141 | 0.77 | PLOD2 (0.53) | DRD2ALDH1A1HPGDSMN1; SMN2SIGMAR1 | |
| SCHEMBL19806639 | 0.77 | ERCC5 (0.55) | ALDH1A1LMNAKDM4E | |
| SCHEMBL4575322 | 0.77 | GSK3B (0.52) | HAO1SMN1; SMN2 | |
| SCHEMBL8610054 | 0.77 | TAS1R3 (0.46) | TAS1R3TAS1R1SLC6A4ALDH1A1HPGD | |
| SCHEMBL4707187 | 0.77 | HAO1 (0.62) | HAO1PLK1TAS1R3TAS1R1MMP2 | |
| SCHEMBL4842868 | 0.77 | HAO1 (0.67) | HAO1PLK1TAS1R3TAS1R1MMP2 | |
| SCHEMBL4251157 | 0.77 | MEN1 (0.61) | HAO1ALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL5187629 | 0.77 | SLC18A3 (0.56) | PLK1ALDH1A1LMNASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524018-B1 | Isoxazole herbicides | RHONE POULENC AGRICULTURE (GB) | 2000-10-18 | — | — | EP | disclosed |
| US-5424276-A | Herbicidal 4-acyl-5-pyridylisoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1995-06-13 | — | — | US | disclosed |
| US-5366957-A | Plant growth regulators | RHONE-POULENC ARGRICULTURE LTD (GB) | 1994-11-22 | — | — | US | disclosed |
| EP-0524018-A1 | Isoxazole herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-01-20 | — | — | EP | disclosed |