Dimethylamine

Dimethylamine

SCHEMBL8109560

CCCCN1CCC(=O)CC1.CCCCN1CCC(=O)CC1.CNC.CNC

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
THRB P10828 1/20 0.42
HPGD P15428 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
DRD2 P14416 2/20 0.41
DRD4 P21917 2/20 0.41
DRD3 P35462 2/20 0.41
CHRM2 P08172 1/20 0.41
CHRM4 P08173 1/20 0.41
CHRM5 P08912 1/20 0.41
CHRM1 P11229 1/20 0.41
CHRM3 P20309 1/20 0.41
HRH3 Q9Y5N1 1/20 0.38
SIGMAR1 Q99720 3/20 0.37
GNAI3 P08754 1/20 0.37
GNAO1 P09471 1/20 0.37
GNAI1 P63096 1/20 0.37
OPRM1 P35372 1/20 0.37
OPRD1 P41143 1/20 0.37
OPRK1 P41145 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylamine SCHEMBL6948646 1.00 ALDH1A1 (0.42) ALDH1A1THRBHPGDL3MBTL1DRD2
Dimethylamine SCHEMBL6950264 0.94 GNAI3 (0.44) GNAI3GNAO1GNAI1S1PR1S1PR3
SCHEMBL8108347 0.94 ALDH1A1 (0.45) ALDH1A1THRBHPGDL3MBTL1DRD2
SCHEMBL3728839 0.94 ALDH1A1 (0.45) ALDH1A1THRBHPGDL3MBTL1DRD2
Hydrochloric Acid SCHEMBL3738666 0.92 ALDH1A1 (0.44) ALDH1A1THRBHPGDL3MBTL1DRD2
Bromide SCHEMBL3726981 0.92 ALDH1A1 (0.44) ALDH1A1THRBHPGDL3MBTL1DRD2
Diethylamine SCHEMBL6944033 0.89 ALDH1A1 (0.40) ALDH1A1THRBHPGDL3MBTL1DRD2
SCHEMBL2412116 0.88 GNAI3 (0.48) GNAI3GNAO1GNAI1S1PR1S1PR3
Dimethylamine SCHEMBL6946290 0.88 POLB (0.42) ALDH1A1THRBL3MBTL1DRD2SIGMAR1
SCHEMBL6947718 0.87 ALDH1A1 (0.39) ALDH1A1THRBHPGDL3MBTL1DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1056744-A1 6,9-DISUBSTITUTED 2- TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES Aventis Pharmaceuticals Inc. (US) 2000-12-06 EP disclosed
WO-1999043675-A1 6,9-DISUBSTITUTED 2-[TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES AVENTIS PHARMACEUTICALS INC. (US) 1999-09-02 WO disclosed