Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.73 |
| ▸ | NPC1 | O15118 | 6/20 | 0.73 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 4/20 | 0.69 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | CASP1 | P29466 | 1/20 | 0.63 |
| ▸ | CASP7 | P55210 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6089260 | 0.90 | ALDH1A1 (0.60) | ALDH1A1NPC1RXFP1NPSR1SMN1; SMN2 | |
| SCHEMBL28480632 | 0.84 | RAB9A (0.74) | ALDH1A1NPC1RXFP1NPSR1SMN1; SMN2 | |
| SCHEMBL3584407 | 0.84 | SMN1; SMN2 (0.80) | ALDH1A1NPC1RXFP1NPSR1SMN1; SMN2 | |
| SCHEMBL4924360 | 0.84 | NPC1 (0.59) | ALDH1A1NPC1RXFP1NPSR1SMN1; SMN2 | |
| SCHEMBL6089264 | 0.84 | ALDH1A1 (0.54) | ALDH1A1NPC1RXFP1NPSR1SMN1; SMN2 | |
| SCHEMBL3582251 | 0.83 | SMN1; SMN2 (1.00) | ALDH1A1NPC1RXFP1NPSR1SMN1; SMN2 | |
| SCHEMBL16607174 | 0.83 | ALDH1A1 (0.75) | ALDH1A1NPC1RXFP1NPSR1SMN1; SMN2 | |
| SCHEMBL31558296 | 0.83 | ALDH1A1 (0.75) | ALDH1A1NPC1RXFP1NPSR1SMN1; SMN2 | |
| SCHEMBL14877171 | 0.83 | ALDH1A1 (0.75) | ALDH1A1NPC1RXFP1NPSR1SMN1; SMN2 | |
| SCHEMBL23742075 | 0.81 | SMN1; SMN2 (0.77) | ALDH1A1NPC1RXFP1NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649843-B1 | THIAZOLINE DERIVATIVE | TAISHO PHARMACEUTICAL CO LTD (JP) | 2000-09-06 | — | — | EP | disclosed |
| US-5672712-A | ANTIAGGLOMERANTS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1997-09-30 | — | — | US | disclosed |
| EP-0765875-A1 | THIAZOLINE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1997-04-02 | — | — | EP | disclosed |
| US-5478945-A | Fibrinogen receptor antagonism and cell adhesion factor antagonism | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1995-12-26 | — | — | US | disclosed |
| EP-0649843-A1 | THIAZOLINE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-04-26 | — | — | EP | disclosed |