Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.39 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1354181 | 0.84 | LMNA (0.40) | ERCC1ERCC4LMNAMAPTNPSR1 | |
| SCHEMBL6760701 | 0.80 | LMNA (0.35) | LMNAMAPTNPSR1HTTCYP1A2 | |
| Hydrochloric Acid SCHEMBL8096376 | 0.79 | IGF1R (0.37) | LMNAMAPTNPSR1HTTHPGD | |
| SCHEMBL580445 | 0.79 | MAPT (0.56) | LMNAMAPTNPSR1HTTHPGD | |
| SCHEMBL10514001 | 0.78 | TSHR (0.43) | LMNAMAPTHPGDPOLBCHRM3 | |
| Bromide SCHEMBL5670305 | 0.78 | MAPT (0.55) | LMNAMAPTNPSR1HTTHPGD | |
| Hydrochloric Acid SCHEMBL8104115 | 0.77 | DPP4 (0.40) | ERCC1ERCC4LMNAMAPTNPSR1 | |
| SCHEMBL5179357 | 0.77 | CHRM3 (0.65) | LMNAMAPTCHRM3ESR1CHRM2 | |
| Mandelic Acid SCHEMBL8096709 | 0.76 | LMNA (0.39) | ERCC1ERCC4LMNAMAPTNPSR1 | |
| SCHEMBL5683062 | 0.76 | IDO1 (0.40) | LMNAMAPTCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019358-A1 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | Pharmacia & Upjohn AB (SE) | 2000-07-19 | — | — | EP | disclosed |
| WO-1998043942-A1 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | PHARMACIA & UPJOHN AB (SE) | 1998-10-08 | — | — | WO | disclosed |