Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1354181 | 0.91 | LMNA (0.40) | LMNACHRM2CHRM1MAPK1CHRM5 | |
| SCHEMBL8096707 | 0.84 | LMNA (0.37) | LMNACHRM2CHRM1MAPK1CHRM5 | |
| Hydrochloric Acid SCHEMBL8104115 | 0.79 | DPP4 (0.40) | LMNACHRM2CHRM1MAPK1CHRM5 | |
| Cadaverine Tartrate SCHEMBL5269127 | 0.79 | CHRM2 (0.62) | LMNACHRM2CHRM1MAPK1CHRM5 | |
| Desfesoterodine SCHEMBL5178331 | 0.78 | CHRM3 (0.65) | LMNACHRM2CHRM1MAPK1CHRM5 | |
| Desfesoterodine SCHEMBL3924814 | 0.78 | CHRM3 (0.65) | LMNACHRM2CHRM1MAPK1CHRM5 | |
| SCHEMBL8109866 | 0.76 | ERCC1 (0.39) | LMNACHRM2CHRM1MAPK1CHRM5 | |
| Hydrochloric Acid SCHEMBL8096376 | 0.76 | IGF1R (0.37) | LMNACHRM2CHRM1MAPK1CHRM5 | |
| SCHEMBL580445 | 0.76 | MAPT (0.56) | LMNACHRM2CHRM1MAPK1CHRM5 | |
| SCHEMBL6760480 | 0.76 | CHRM2 (0.51) | CHRM2CHRM1HPGDMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019358-A1 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | Pharmacia & Upjohn AB (SE) | 2000-07-19 | — | — | EP | disclosed |
| WO-1998043942-A1 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | PHARMACIA & UPJOHN AB (SE) | 1998-10-08 | — | — | WO | disclosed |