Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095063 | 0.92 | HSD11B1 (0.40) | SIGMAR1ALDH1A1HSD11B1DPP8DPP9 | |
| SCHEMBL8095227 | 0.92 | HSD11B1 (0.40) | SIGMAR1ALDH1A1HSD11B1DPP8DPP9 | |
| SCHEMBL8102759 | 0.89 | HSD11B1 (0.34) | SIGMAR1ALDH1A1HSD11B1DPP8DPP9 | |
| SCHEMBL8104577 | 0.87 | DPP8 (0.36) | ALDH1A1DPP8DPP9LMNA | |
| SCHEMBL8102742 | 0.85 | HSD11B1 (0.44) | SIGMAR1ALDH1A1HSD11B1DPP8DPP9 | |
| SCHEMBL8095391 | 0.85 | HSD11B1 (0.44) | SIGMAR1ALDH1A1HSD11B1DPP8DPP9 | |
| SCHEMBL8104555 | 0.85 | HSD11B1 (0.44) | SIGMAR1ALDH1A1HSD11B1DPP8DPP9 | |
| SCHEMBL8104700 | 0.85 | HSD11B1 (0.44) | SIGMAR1ALDH1A1HSD11B1DPP8DPP9 | |
| SCHEMBL8102654 | 0.84 | HSD11B1 (0.37) | SIGMAR1ALDH1A1HSD11B1DPP8DPP9 | |
| SCHEMBL8540671 | 0.83 | HSD11B1 (0.36) | SIGMAR1ALDH1A1HSD11B1DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090802-A | BACTERICIDE | SANKYO COMPANY, LIMITED (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0882728-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-09 | — | — | EP | disclosed |