Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 2/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.31 |
| ▸ | CCR2 | P41597 | 2/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095120 | 0.90 | SIGMAR1 (0.38) | HSD11B1DPP8DPP9SIGMAR1EPHX2 | |
| SCHEMBL8540343 | 0.89 | HSD11B1 (0.36) | HSD11B1DPP8DPP9SIGMAR1EPHX2 | |
| SCHEMBL8540340 | 0.89 | HSD11B1 (0.36) | HSD11B1DPP8DPP9SIGMAR1EPHX2 | |
| SCHEMBL8537617 | 0.89 | HSD11B1 (0.36) | HSD11B1DPP8DPP9SIGMAR1EPHX2 | |
| SCHEMBL8537616 | 0.89 | HSD11B1 (0.36) | HSD11B1DPP8DPP9SIGMAR1EPHX2 | |
| SCHEMBL8095227 | 0.88 | HSD11B1 (0.40) | HSD11B1DPP8DPP9SIGMAR1EPHX2 | |
| SCHEMBL8095063 | 0.88 | HSD11B1 (0.40) | HSD11B1DPP8DPP9SIGMAR1EPHX2 | |
| SCHEMBL8102914 | 0.88 | DPP8 (0.37) | DPP8DPP9CCR5ALDH1A1MAPT | |
| SCHEMBL8102893 | 0.88 | DPP8 (0.37) | DPP8DPP9CCR5ALDH1A1MAPT | |
| SCHEMBL8104555 | 0.85 | HSD11B1 (0.44) | HSD11B1DPP8DPP9SIGMAR1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882728-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-09 | — | — | EP | disclosed |