⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17202583 | 1.00 | — | — | |
| SCHEMBL15514140 | 0.78 | — | — | |
| SCHEMBL2104112 | 0.75 | — | — | |
| SCHEMBL17729867 | 0.75 | — | — | |
| SCHEMBL1557 | 0.73 | — | — | |
| SCHEMBL18011037 | 0.73 | — | — | |
| SCHEMBL333796 | 0.73 | — | — | |
| SCHEMBL6704060 | 0.73 | — | — | |
| SCHEMBL28521 | 0.71 | — | — | |
| SCHEMBL80383 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240101573-A1 | MACROCYCLIC K-RAS G12C INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2024-03-28 | — | — | US | claimed |
| EP-4265610-A1 | MACROCYCLIC K-RAS G12C INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2023-10-25 | — | — | EP | claimed |
| CN-116249703-A | Macrocyclic K-RAS G12C inhibitor, preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2023-06-09 | — | — | CN | claimed |
| CN-111635373-B | Polycyclic sulfonamide ROR gamma modulators | 山东轩竹医药科技有限公司 | 2022-07-12 | — | — | CN | claimed |
| CN-111635373-A | Polycyclic sulfonamide ROR gamma modulators | 山东轩竹医药科技有限公司 | 2020-09-08 | — | — | CN | claimed |
| US-8367838-B2 | Amines or amino alcohols as GLYT1 inhibitors | HOFFMANN-LA ROCHE INC. (US) | 2013-02-05 | — | — | US | claimed |
| US-20120232033-A1 | AMINES OR AMINO ALCOHOLS AS GLYT1 INHIBITORS | KOLCZEWSKI SABINE (DE) | 2012-09-13 | — | — | US | claimed |
| EP-2398558-A1 | AMINE OR AMINO ALCOHOLS AS GLYT1 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2011-12-28 | — | — | EP | claimed |
| WO-2010094659-A1 | AMINE OR AMINO ALCOHOLS AS GLYT1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-08-26 | — | — | WO | claimed |
| US-20100210592-A1 | AMINES OR AMINO ALCOHOLS AS GLYT1 INHIBITORS | HOFFMANN-LA ROCHE, INC. | 2010-08-19 | — | — | US | claimed |
| EP-4393907-A1 | POTASSIUM CHANNEL MODULATOR, COMPOSITION AND APPLICATION | Neushen Therapeutics (Shanghai) Co., Ltd (CN) | 2024-07-03 | — | — | EP | disclosed |
| EP-4387977-A1 | PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2024-06-26 | — | — | EP | disclosed |
| CN-117858881-A | Phospholipid compounds and methods of making and using the same | 吉利德科学公司 | 2024-04-09 | — | — | CN | disclosed |
| US-20240101573-A1 | MACROCYCLIC K-RAS G12C INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2024-03-28 | — | — | US | disclosed |
| WO-2024051696-A1 | COMPOUND FOR RNA CAPPING AND USE THEREOF | 广州市恒诺康医药科技有限公司 | 2024-03-14 | — | — | WO | disclosed |
| US-20030109498-A1 | Antiviral agent for drug-resistant virus | MITSUBISHI PHARMA CORPORATION (JP) | 2003-06-12 | — | — | US | disclosed |
| EP-0785208-B1 | Phosphonate nucleotide compounds | MITSUBISHI CHEM CORP (JP) | 2001-03-21 | — | — | EP | disclosed |
| US-5840716-A | ANTIVIRAL AGENTS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-11-24 | — | — | US | disclosed |
| EP-0785208-A1 | Phosphonate nucleotide compounds | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |
| EP-0365925-A1 | Pyrazole amides and insecticide and miticide containing them as active ingredient | Mitsubishi Chemical Corporation (JP) | 1990-05-02 | — | — | EP | disclosed |