Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 4/20 | 0.36 |
| ▸ | MMP1 | P03956 | 3/20 | 0.35 |
| ▸ | MMP2 | P08253 | 3/20 | 0.35 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.34 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.34 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.34 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8112501 | 0.95 | KMT2A (0.38) | ALDH1A1KMT2ASCN5ASCN2ACNR1 | |
| SCHEMBL8114831 | 0.91 | EPOR (0.39) | ALDH1A1KMT2ACNR1CNR2BLM | |
| SCHEMBL8119518 | 0.87 | EPOR (0.37) | EPORCTSD | |
| SCHEMBL8126911 | 0.86 | NPY1R (0.39) | — | |
| SCHEMBL8120799 | 0.84 | EPOR (0.42) | ALDH1A1KMT2AEPORCTSD | |
| SCHEMBL8120680 | 0.83 | CNR1 (0.36) | CNR1CNR2 | |
| SCHEMBL8127365 | 0.83 | LMNA (0.41) | ALDH1A1KMT2AMAPTCTSD | |
| SCHEMBL8125364 | 0.82 | KMT2A (0.42) | ALDH1A1KMT2ASCN5ASCN2ABLM | |
| SCHEMBL8526325 | 0.82 | MAPT (0.35) | ALDH1A1KMT2AMAPTEPORCTSD | |
| SCHEMBL8125877 | 0.81 | MEN1 (0.46) | ALDH1A1KMT2ABLMMAPTCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |