Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | EPOR | P19235 | 3/20 | 0.35 |
| ▸ | NPY1R | P25929 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8114831 | 0.91 | EPOR (0.39) | NPSR1EPORALDH1A1TDP1KMT2A | |
| SCHEMBL8119581 | 0.89 | NPY1R (0.40) | EPORNPY1R | |
| SCHEMBL8126142 | 0.89 | TDP1 (0.35) | MAPTHTTNPSR1EPORNPY1R | |
| SCHEMBL8127365 | 0.88 | LMNA (0.41) | MAPTHTTNPSR1ALDH1A1MEN1 | |
| SCHEMBL7038692 | 0.87 | OPRM1 (0.34) | MAPTHTTNPSR1EPORNPY1R | |
| SCHEMBL8120746 | 0.87 | TDP1 (0.34) | EPORNPY1RTDP1MC4RMEN1 | |
| SCHEMBL8119418 | 0.87 | NPY1R (0.32) | MAPTHTTNPSR1EPORNPY1R | |
| SCHEMBL8122527 | 0.87 | NPY1R (0.38) | EPORNPY1R | |
| SCHEMBL8120388 | 0.86 | NR3C2 (0.34) | EPORNPY1RTDP1 | |
| SCHEMBL8112912 | 0.86 | CTSD (0.36) | MAPTHTTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |