Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 6/20 | 0.68 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 7/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 6/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9054177 | 0.88 | MCL1 (0.60) | MCL1BCL2L1FABP4FABP5CYP2C9 | |
| SCHEMBL8356540 | 0.88 | MCL1 (0.56) | MCL1BCL2L1FABP4FABP5CYP2C9 | |
| SCHEMBL9110910 | 0.83 | MCL1 (0.54) | MCL1BCL2L1FABP4FABP5CYP2C9 | |
| SCHEMBL9111493 | 0.82 | MCL1 (0.56) | MCL1BCL2L1FABP4FABP5CYP2C9 | |
| SCHEMBL30076571 | 0.81 | MCL1 (1.00) | MCL1BCL2L1CYP2C9HSD17B10HPGD | |
| SCHEMBL18392411 | 0.81 | MCL1 (1.00) | MCL1BCL2L1CYP2C9HSD17B10HPGD | |
| SCHEMBL9056913 | 0.76 | CYP1A1 (0.49) | MCL1BCL2L1FABP4FABP5CYP2C9 | |
| SCHEMBL30076600 | 0.76 | MCL1 (1.00) | MCL1BCL2L1ALDH1A1 | |
| SCHEMBL18392242 | 0.76 | MCL1 (1.00) | MCL1BCL2L1ALDH1A1 | |
| SCHEMBL28981270 | 0.76 | MCL1 (0.66) | MCL1FABP4FABP5CYP2C9HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861252-B1 | NAPHTHAMIDE DERIVATIVES OF 3 BETA-AMINO AZABICYCLO OCTANE OR NONANE AS NEUROLEPTIC AGENTS | PF MEDICAMENT (FR) | 2000-02-23 | — | — | EP | disclosed |
| EP-0944314-A1 | METHYL SUBSTITUTED FUNGICIDES AND ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-09-29 | — | — | EP | disclosed |
| US-5958945-A | PSYCHOLOGICAL DISORDERS | PIERRE FABRE MEDICAMENT (FR) | 1999-09-28 | — | — | US | disclosed |
| WO-1998023156-A1 | METHYL SUBSTITUTED FUNGICIDES AND ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-06-04 | — | — | WO | disclosed |
| WO-1995010504-A1 | 2-(1-ALKOXY-2-NAPHTHALENYL)-PYRROLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINE D3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-04-20 | — | — | WO | disclosed |