Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.54 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 11/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 9/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056913 | 0.92 | CYP1A1 (0.49) | MCL1BCL2L1FABP4FABP5CYP2C9 | |
| SCHEMBL9111493 | 0.84 | MCL1 (0.56) | MCL1BCL2L1FABP4FABP5CYP2C9 | |
| SCHEMBL8112005 | 0.83 | MCL1 (0.68) | MCL1BCL2L1FABP4FABP5CYP2C9 | |
| SCHEMBL15313666 | 0.81 | HSD17B10 (0.46) | MCL1HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL9054177 | 0.80 | MCL1 (0.60) | MCL1BCL2L1FABP4FABP5CYP2C9 | |
| SCHEMBL7234615 | 0.78 | MCL1 (0.71) | MCL1BCL2L1CYP2C9HSD17B10KDM4E | |
| SCHEMBL29539793 | 0.78 | MCL1 (0.71) | MCL1BCL2L1CYP2C9HSD17B10KDM4E | |
| SCHEMBL8967049 | 0.78 | ALDH1A1 (0.60) | MCL1HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL976330 | 0.76 | KDM4E (0.57) | CYP2C9HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL669832 | 0.76 | THRB (0.61) | MCL1CYP2C9HSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995016674-A1 | AMINOSULPHONYL-PHENYL-1H-PYRROLE DERIVATIVES, METHOD OF THEIR PREPARATION AND THEIR USE | SMITHKLINE BEECHAM PLC (GB) | 1995-06-22 | — | — | WO | disclosed |
| WO-1995010504-A1 | 2-(1-ALKOXY-2-NAPHTHALENYL)-PYRROLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINE D3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-04-20 | — | — | WO | disclosed |