Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8112005 | 0.88 | MCL1 (0.68) | MCL1KDM4EALDH1A1HPGDFABP4 | |
| SCHEMBL7774895 | 0.83 | ALDH1A1 (0.57) | MCL1KDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL7774891 | 0.82 | KDM4E (0.52) | MCL1KDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL8967057 | 0.77 | KDM4E (0.56) | KDM4EALDH1A1HPGDNPSR1L3MBTL1 | |
| SCHEMBL30076588 | 0.77 | MCL1 (0.83) | MCL1KDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL18392304 | 0.77 | MCL1 (0.83) | MCL1KDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL9054177 | 0.76 | MCL1 (0.60) | MCL1KDM4EKMT2AFABP4FABP5 | |
| SCHEMBL6627930 | 0.76 | CA1 (0.65) | MCL1KDM4EALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL3741758 | 0.75 | KDM4E (0.60) | KDM4EALDH1A1HPGDNPSR1L3MBTL1 | |
| SCHEMBL8966782 | 0.74 | KDM4E (0.59) | KDM4EALDH1A1HPGDNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958945-A | PSYCHOLOGICAL DISORDERS | PIERRE FABRE MEDICAMENT (FR) | 1999-09-28 | — | — | US | disclosed |