Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CCR3 | P51677 | 4/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8118416 | 0.93 | SIGMAR1 (0.70) | SIGMAR1DRD3 | |
| SCHEMBL8120545 | 0.92 | SIGMAR1 (0.62) | SIGMAR1DRD3 | |
| SCHEMBL8119845 | 0.87 | SIGMAR1 (0.64) | SIGMAR1DRD3CCR3CYP2D6MEN1 | |
| SCHEMBL8111456 | 0.87 | SIGMAR1 (0.80) | SIGMAR1DRD3 | |
| SCHEMBL8120491 | 0.83 | SIGMAR1 (0.74) | SIGMAR1DRD3MEN1KMT2A | |
| SCHEMBL8126235 | 0.80 | SIGMAR1 (0.75) | SIGMAR1DRD3 | |
| SCHEMBL8120009 | 0.80 | SIGMAR1 (0.75) | SIGMAR1DRD3 | |
| SCHEMBL8127075 | 0.80 | SIGMAR1 (0.75) | SIGMAR1DRD3 | |
| SCHEMBL8124961 | 0.79 | SIGMAR1 (0.74) | SIGMAR1DRD3 | |
| SCHEMBL8120171 | 0.79 | SIGMAR1 (0.93) | SIGMAR1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861252-B1 | NAPHTHAMIDE DERIVATIVES OF 3 BETA-AMINO AZABICYCLO OCTANE OR NONANE AS NEUROLEPTIC AGENTS | PF MEDICAMENT (FR) | 2000-02-23 | — | — | EP | claimed |