Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9595485 | 0.85 | GBA2 (0.30) | — | |
| SCHEMBL9399785 | 0.84 | GPR119 (0.33) | GPR119HSD11B1NR1H3NR1H2 | |
| SCHEMBL5434124 | 0.81 | GPR119 (0.34) | GPR119HSD11B1NR1H3NR1H2 | |
| SCHEMBL2080999 | 0.81 | GPR119 (0.34) | GPR119HSD11B1NR1H3NR1H2 | |
| SCHEMBL2200885 | 0.81 | GPR119 (0.34) | GPR119HSD11B1NR1H3NR1H2 | |
| SCHEMBL8690955 | 0.81 | GPR119 (0.34) | GPR119HSD11B1NR1H3NR1H2 | |
| SCHEMBL8107979 | 0.77 | NR1H2 (0.36) | NR1H2 | |
| SCHEMBL9595771 | 0.77 | NR1H2 (0.36) | NR1H2 | |
| SCHEMBL9399506 | 0.77 | NR1H2 (0.36) | NR1H2 | |
| SCHEMBL8759135 | 0.77 | NR1H2 (0.32) | NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545290-B1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMA CO LTD (JP) | 2000-08-23 | — | — | EP | disclosed |
| US-5550121-A | ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| US-5374720-A | A thienamycins bactericides has nontoxic, side effect reduction against the kidney and central nervous system | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0545290-A1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |