Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 4/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8112473 | 1.00 | CHRNB2 (0.50) | CHRNB2CHRNA4ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7993578 | 0.81 | CHRNB2 (0.54) | CHRNB2CHRNA4ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7993571 | 0.81 | CHRNB2 (0.54) | CHRNB2CHRNA4ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7992330 | 0.75 | CHRNB2 (0.52) | CHRNB2CHRNA4ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7992326 | 0.75 | CHRNB2 (0.52) | CHRNB2CHRNA4ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7981981 | 0.74 | CHRNB2 (0.64) | CHRNB2CHRNA4ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5193562 | 0.74 | CHRNB2 (0.47) | CHRNB2CHRNA4ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8011665 | 0.74 | CHRNB2 (0.64) | CHRNB2CHRNA4ALDH1A1MAPTSMN1; SMN2 | |
| Imidacloprid SCHEMBL22278 | 0.73 | ALDH1A1 (0.64) | CHRNB2CHRNA4ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL238913 | 0.73 | CHRNB2 (0.55) | CHRNB2CHRNA4ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685477-B1 | Insecticidal tetrahydrofuran-compound | MITSUI CHEMICALS INC (JP) | 2000-10-18 | — | — | EP | disclosed |
| EP-0685477-A1 | Insecticidal tetrahydrofuran-compound | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1995-12-06 | — | — | EP | disclosed |