Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30785465 | 0.81 | IKBKB (0.42) | SLC6A4IDH1 | |
| Hydrochloric Acid SCHEMBL27158432 | 0.80 | IKBKB (0.41) | SLC6A4IDH1 | |
| Hydrochloric Acid SCHEMBL27158231 | 0.79 | KDM1A (0.48) | SLC6A4KCNH2 | |
| SCHEMBL30785443 | 0.78 | KCNH2 (0.40) | HTR2CSLC6A4HTR2BHCRTR1HCRTR2 | |
| SCHEMBL30785441 | 0.77 | HTR2C (0.41) | HTR2CSLC6A4HTR2BHCRTR1HCRTR2 | |
| SCHEMBL27158587 | 0.77 | HTR2C (0.41) | HTR2CSLC6A4HTR2BHCRTR1HCRTR2 | |
| SCHEMBL27157901 | 0.77 | HTR2C (0.41) | HTR2CSLC6A4HTR2BHCRTR1HCRTR2 | |
| SCHEMBL27158591 | 0.77 | HTR2C (0.41) | HTR2CSLC6A4HTR2BHCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL27157954 | 0.77 | KCNH2 (0.39) | HTR2CSLC6A4HTR2BHCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL27157860 | 0.76 | HTR2C (0.40) | HTR2CSLC6A4HTR2BHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |