Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.38 |
| ▸ | IDH1 | O75874 | 3/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.35 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | IDH2 | P48735 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27157954 | 0.99 | KCNH2 (0.39) | KCNH2SYKAURKBHCRTR2IDH1 | |
| Hydrochloric Acid SCHEMBL30328888 | 0.81 | HCRTR2 (0.35) | KCNH2HCRTR2IDH1HCRTR1SLC6A4 | |
| Hydrochloric Acid SCHEMBL30329324 | 0.79 | HCRTR2 (0.34) | KCNH2HCRTR2IDH1HCRTR1SLC6A4 | |
| SCHEMBL8112751 | 0.78 | LTA4H (0.45) | KCNH2HCRTR2IDH1HCRTR1SLC6A4 | |
| Hydrochloric Acid SCHEMBL30329505 | 0.77 | PIM1 (0.37) | KCNH2HCRTR2IDH1HCRTR1SLC6A4 | |
| SCHEMBL30785465 | 0.77 | IKBKB (0.42) | IDH1SLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL27158432 | 0.76 | IKBKB (0.41) | IDH1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL30785441 | 0.76 | HTR2C (0.41) | KCNH2HCRTR2IDH1HCRTR1SLC6A4 | |
| SCHEMBL27158587 | 0.76 | HTR2C (0.41) | KCNH2HCRTR2IDH1HCRTR1SLC6A4 | |
| SCHEMBL27157901 | 0.76 | HTR2C (0.41) | KCNH2HCRTR2IDH1HCRTR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117642404-A | Small molecule modulators of glucocerebrosidase activity and uses thereof | 凡况生化公司 | 2024-03-01 | — | — | CN | disclosed |