Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | HTR2B | P41595 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27158591 | 1.00 | HTR2C (0.41) | HTR2CHTR2BSLC6A4RXRAHCRTR2 | |
| SCHEMBL27157901 | 1.00 | HTR2C (0.41) | HTR2CHTR2BSLC6A4RXRAHCRTR2 | |
| SCHEMBL27158587 | 1.00 | HTR2C (0.41) | HTR2CHTR2BSLC6A4RXRAHCRTR2 | |
| Hydrochloric Acid SCHEMBL27157860 | 0.99 | HTR2C (0.40) | HTR2CHTR2BSLC6A4RXRAHCRTR2 | |
| Hydrochloric Acid SCHEMBL27204278 | 0.99 | HTR2C (0.40) | HTR2CHTR2BSLC6A4RXRAHCRTR2 | |
| SCHEMBL8112751 | 0.77 | LTA4H (0.45) | HTR2CHTR2BSLC6A4RXRAHCRTR2 | |
| SCHEMBL27158488 | 0.77 | HCRTR2 (0.41) | RXRAHCRTR2HCRTR1GRIN1GRIN2B | |
| SCHEMBL27204297 | 0.77 | HCRTR2 (0.41) | RXRAHCRTR2HCRTR1GRIN1GRIN2B | |
| Hydrochloric Acid SCHEMBL27158231 | 0.77 | KDM1A (0.48) | SLC6A4KCNH2 | |
| SCHEMBL30785465 | 0.76 | IKBKB (0.42) | SLC6A4FEN1IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117642404-A | Small molecule modulators of glucocerebrosidase activity and uses thereof | 凡况生化公司 | 2024-03-01 | — | — | CN | disclosed |