Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9666422 | 1.00 | KDM4E (0.66) | KDM4EPTGES | |
| SCHEMBL9651625 | 1.00 | KDM4E (0.66) | KDM4EPTGES | |
| SCHEMBL9370590 | 0.99 | KDM4E (0.67) | KDM4EPTGES | |
| SCHEMBL9666017 | 0.90 | KDM4E (0.60) | KDM4EPTGES | |
| SCHEMBL9370221 | 0.90 | KDM4E (0.62) | KDM4EPTGES | |
| SCHEMBL13516893 | 0.89 | KDM4E (0.72) | KDM4EPTGES | |
| SCHEMBL9217701 | 0.89 | ACAT1 (0.66) | KDM4E | |
| SCHEMBL9212895 | 0.89 | ACAT1 (0.66) | KDM4E | |
| SCHEMBL9213347 | 0.89 | ACAT1 (0.66) | KDM4E | |
| SCHEMBL9210387 | 0.88 | KDM4E (0.64) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0359197-B1 | ANTIHYPERCHOLESTEROLEMIC 4,5-DIARYL-2-SUBSTITUTED THIOIMIDAZOLES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-12-23 | — | — | EP | claimed |
| EP-0359197-A1 | Antihypercholesterolemic 4,5-diaryl-2-substituted thioimidazoles | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1990-03-21 | — | — | EP | claimed |
| US-4900744-A | Antihypercholesterolemic 4,5-diaryl-2-substituted thioimidazoles | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-02-13 | — | — | US | claimed |
| EP-0626969-B1 | CoA-IT AND PAF INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2000-05-24 | — | — | EP | disclosed |
| US-5663053-A | COENZYME A TRANSACYLASE FOR SCREENING | SMITHKLINE BEECHAM CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
| US-5648373-A | CoA-IT and PAF inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-15 | — | — | US | disclosed |
| EP-0626969-A4 | CoA-IT AND PAF INHIBITORS. | SMITHKLINE BEECHAM CORP (US) | 1995-04-19 | — | — | EP | disclosed |
| EP-0626969-A1 | CoA-IT AND PAF INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-12-07 | — | — | EP | disclosed |
| US-5318984-A | Anticholesterol agents which inhibit acetyl coenzyme A transferase | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-06-07 | — | — | US | disclosed |
| EP-0372445-B1 | Imidazoles for the treatment of atherosclerosis | DU PONT MERCK PHARMA (US) | 1994-03-09 | — | — | EP | disclosed |
| WO-1993016674-A1 | CoA-IT AND PAF INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-09-02 | — | — | WO | disclosed |
| EP-0359197-B1 | ANTIHYPERCHOLESTEROLEMIC 4,5-DIARYL-2-SUBSTITUTED THIOIMIDAZOLES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-12-23 | — | — | EP | disclosed |
| US-5166214-A | Enzyme inhibitors for anticholesterol agents, enzyme inhibitor and cardiovascular disorders | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-11-24 | — | — | US | disclosed |
| WO-1991018885-A1 | IMIDAZOLES FOR THE TREATMENT OF ATHEROSCLEROSIS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-12-12 | — | — | WO | disclosed |
| EP-0372445-A1 | Imidazoles for the treatment of atherosclerosis | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1990-06-13 | — | — | EP | disclosed |
| EP-0359197-A1 | Antihypercholesterolemic 4,5-diaryl-2-substituted thioimidazoles | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1990-03-21 | — | — | EP | disclosed |
| US-4900744-A | Antihypercholesterolemic 4,5-diaryl-2-substituted thioimidazoles | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-02-13 | — | — | US | disclosed |