Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3174806 | 0.92 | KDM4E (0.65) | KDM4EPTGES | |
| SCHEMBL9370590 | 0.91 | KDM4E (0.67) | KDM4EPTGES | |
| SCHEMBL8112795 | 0.90 | KDM4E (0.66) | KDM4EPTGES | |
| SCHEMBL9666422 | 0.90 | KDM4E (0.66) | KDM4EPTGES | |
| SCHEMBL9651625 | 0.90 | KDM4E (0.66) | KDM4EPTGES | |
| SCHEMBL9210387 | 0.88 | KDM4E (0.64) | KDM4E | |
| SCHEMBL9666017 | 0.88 | KDM4E (0.60) | KDM4EPTGES | |
| SCHEMBL9217701 | 0.86 | ACAT1 (0.66) | KDM4E | |
| SCHEMBL9212895 | 0.86 | ACAT1 (0.66) | KDM4E | |
| SCHEMBL9213347 | 0.86 | ACAT1 (0.66) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5318984-A | Anticholesterol agents which inhibit acetyl coenzyme A transferase | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-06-07 | — | — | US | disclosed |
| EP-0372445-B1 | Imidazoles for the treatment of atherosclerosis | DU PONT MERCK PHARMA (US) | 1994-03-09 | — | — | EP | disclosed |
| EP-0372445-A1 | Imidazoles for the treatment of atherosclerosis | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1990-06-13 | — | — | EP | disclosed |